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The mystery of a Florida hotel owner's disappearance confounds family, friends and the detectives investigating the case.

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A wife and mother survives an attack in her home and a shot to the head; authorities search for a motive.

When a complicated Texas love triangle ends in murder, a pink gun leads to an arrest, until new evidence prompts investigators to rethink the case.

A son uncovers a dark family conspiracy when he questions his mother following a man's apparent suicide.

A luxury car salesman is asked by a beautiful former client to plan a murder.

The discovery of an Army captain's death in her El Paso, Texas, home shakes her tight-knit military community.

A look at the growing homeless epidemic in America, including a tour of Skid Row, the nation's epicenter of homelessness; residents of the San Fernando Valley and Venice discuss the influx of homeless people into their neighborhoods.

A young father in California calls 911 after being in a shootout in a car full of strangers that injures two people and kills another.

It was called "the trial of the century" and, decades after the polarizing case, questions remain; hear answers and insights through interviews done over the years, rare footage and revealing conversations with key players who offer new details.

A community comes together to search for a young woman who goes missing from a Halloween party.

The trial and murder conviction of Jodi Arias and the salacious relationship that ended in tragedy.

A teenager is convicted of encouraging her boyfriend to kill himself; exclusive interviews with those on both sides of the case.

A traumatic secret tears a family apart after 27 years.

When a millionaire is found dead in the trunk of her car, authorities become suspicious of her ex-husband.

An intruder breaks into a lawyer's home, murders his wife and blinds him; in a search for the truth, the lawyer questions his troubled son as a possible suspect.

After finding his wife and two children dead, a former Indiana state trooper spends 13 years trying to clear his name.

Police initially suspect natural causes as they investigate a man's death, until they learn about an unconventional love triangle, which points the investigation in a new direction.

A man dies in a shooting incident after tempers flare in a confrontation in Montana's Glacier National Park.

Police suspect a murder-for-hire plot when a realtor is attacked and left for dead at a home showing and begin investigating his family and business partners.